ANAHEIM -- It looked like the Mariners were on their way to a much-needed series win over the Angels on Saturday, but despite the offense's momentum, they were unable to capitalize on scoring opportunities in the late innings and walked away with a 5-4 loss at Angel Stadium.

The Angels got the last word as outfielder Mickey Moniak launched his first career walk-off home run, against Andr¨¦s Mu?oz in the ninth inning.

"I thought our at-bats were great -- a lot of good contact, some patience at the plate as well, a couple of walks that got us into good positions," said manager Dan Wilson. "It's just a tough one to walk away from. Coming up on the wrong end of a walk-off is hard."

This season, the Halos have proved to be quite a competitor for Seattle. The Angels swept the Mariners in July and won three of four games in Anaheim leading up to the All-Star break. Wilson has emphasized how important it is for the team's offense to fight through nine innings, and while their efforts did not result in a win, their progress on that goal is not lost.

"They fought till the end," Wilson said. "No doubt about it, these guys put up some great at-bats, good defense. Just a couple of guys in that lineup that got to us tonight, but it was a hard-fought fight all the way to the end. We'll put this one aside. Come back tomorrow, ready to play."

Justin Turner kickstarted the offense with two solo home runs, marking his 17th career multi-home run game and his first as a Mariner. He set the tone for an early offensive push against left-handed pitcher Tyler Anderson, one of the Angels' more consistent starting arms.

Turner wasn't the only Mariner to find his groove at the plate. Following his lead, the team strung together a productive fourth inning. Dylan Moore reached first on a line drive to left field and stayed aggressive on the basepaths, stealing his 28th base on the season and his 100th career stolen base. Victor Robles and J.P. Crawford both drew walks, setting the stage for Julio Rodr¨ªguez, who has been electric at the plate this road trip.

Against the Angels on Friday, Rodr¨ªguez went 1-for-2 with three runs, a home run and three walks. On Saturday, he showed more of that productivity. Rodr¨ªguez reached base four times with three hits and one walk, including a line drive to left field in the fourth that scored Robles and Crawford and gave the team some early insurance behind starting pitcher Bryan Woo.

Woo, who has focused on pitching deeper into games this season, pitched 6 1/3 innings but struggled to keep the Angels' offense at bay. He allowed two solo homers to outfielder Jo Adell and a two-run blast to Moniak in the seventh, leaving the score tied at 4-4.

"I think it's just some three-strike mistakes and leaving balls over the middle," Woo said. "I feel like early on, I attacked the middle of the zone and tried to expand late, and I just didn't do that."

After successfully shutting down an attempted squeeze play in the eighth, the Mariners were primed to take back the lead, but it didn't turn out that way. In the ninth, Seattle faced closer Ben Joyce, known for clocking pitches over 103 mph. Randy Arozarena was hit by a pitch and Turner followed up with his third hit of the night, but the two runners were left stranded, closing the chapter on yet another loss to the Angels.

"It was a big play for sure -- huge two outs there," catcher Cal Raleigh said. "I've never really seen that play before. It was kind of crazy. We had good momentum, got some people on there in the ninth and had a chance. Just couldn't do it."

Seattle is now 4 1/2 games back of the Houston Astros in the AL West. They'll have one more chance to take the series against the Angels on Sunday behind Bryce Miller, who is looking for his 11th win.