Guardians Roster & Staff
Transactions
| Date | Transaction |
| 03/25/25 | LHP Izaak Martinez assigned to Cleveland Guardians. |
| 03/24/25 | Cleveland Guardians optioned RF Will Brennan to Columbus Clippers. |
| 03/24/25 | Cleveland Guardians optioned RHP Andrew Walters to Columbus Clippers. |
| 03/22/25 | Colorado Rockies traded LF Nolan Jones to Cleveland Guardians for CF Tyler Freeman. |
| 03/22/25 | Colorado Rockies traded LF Nolan Jones to Cleveland Guardians for CF Tyler Freeman. |
| 03/21/25 | SS Fran Alduey assigned to Cleveland Guardians. |
| 03/21/25 | Cleveland Guardians optioned RF Johnathan Rodriguez to Columbus Clippers. |
| 03/21/25 | Cleveland Guardians optioned SS Juan Brito to Columbus Clippers. |
| 03/21/25 | Cleveland Guardians optioned CF Angel Mart¨ªnez to Columbus Clippers. |
| 03/20/25 | SS Christian Cairo returned to Cleveland Guardians from Atlanta Braves. |
| 03/19/25 | SS Yanki Baptiste assigned to Cleveland Guardians. |
| 03/19/25 | OF Robert Arias assigned to Cleveland Guardians. |
| 03/19/25 | SS Gabriel Rodriguez assigned to Cleveland Guardians. |
| 03/19/25 | C Reiner Herrera assigned to Cleveland Guardians. |
| 03/17/25 | C David Leon assigned to Cleveland Guardians. |
| 03/16/25 | RF Wuilfredo Antunez assigned to Cleveland Guardians. |
| 03/16/25 | C Robert Lopez assigned to Cleveland Guardians. |
| 03/15/25 | SS Welbyn Francisca assigned to Cleveland Guardians. |
| 03/15/25 | Cleveland Guardians signed free agent 3B Kyle Datres to a minor league contract. |
| 03/15/25 | Cleveland Guardians optioned LHP Doug Nikhazy to Columbus Clippers. |
| 03/14/25 | LHP Shawn Rapp assigned to Cleveland Guardians. |
| 03/14/25 | LHP Adam Tulloch assigned to Cleveland Guardians. |
| 03/14/25 | 2B Maick Collado assigned to Cleveland Guardians. |
| 03/14/25 | RF Carlos Gutierrez assigned to Cleveland Guardians. |
| 03/14/25 | C Victor Izturis assigned to Cleveland Guardians. |
| 03/14/25 | 2B Juan Benjamin assigned to Cleveland Guardians. |
| 03/14/25 | 3B Jeffrey Mercedes assigned to Cleveland Guardians. |
| 03/13/25 | OF Yeiferth Castillo assigned to Cleveland Guardians. |
| 03/13/25 | LF Esteban Gonzalez assigned to Cleveland Guardians. |
| 03/13/25 | 2B Dauri Fernandez assigned to Cleveland Guardians. |
| 03/12/25 | RHP Xavier Martinez assigned to Cleveland Guardians. |
| 03/12/25 | Cleveland Guardians optioned CF Petey Halpin to Columbus Clippers. |
| 03/11/25 | RHP Robert Wegielnik assigned to Cleveland Guardians. |
| 03/11/25 | 2B Alberto Mendez assigned to Cleveland Guardians. |
| 03/11/25 | RHP Reny Artiles assigned to Cleveland Guardians. |
| 03/11/25 | CF Jose Pirela assigned to Cleveland Guardians. |
| 03/10/25 | C Bennett Thompson assigned to Cleveland Guardians. |
| 03/10/25 | OF Ryan Cesarini assigned to Cleveland Guardians. |
| 03/10/25 | 2B Jonathan Martinez assigned to Cleveland Guardians. |
| 03/10/25 | CF Yerlin Luis assigned to Cleveland Guardians. |
| 03/10/25 | LF Isaiah Greene assigned to Cleveland Guardians. |
| 03/10/25 | SS Garrett Howe assigned to Cleveland Guardians. |
| 03/10/25 | LF Heribert Silva assigned to Cleveland Guardians. |
| 03/09/25 | 3B Michael Hallquist assigned to Cleveland Guardians. |
| 03/09/25 | LF Tommy Hawke assigned to Cleveland Guardians. |
| 03/09/25 | C Johnny Tincher assigned to Cleveland Guardians. |
| 03/09/25 | 1B Ralphy Velazquez assigned to Cleveland Guardians. |
| 03/08/25 | C Manuel Mejias assigned to Cleveland Guardians. |
| 03/08/25 | RHP Alonzo Richardson assigned to Cleveland Guardians. |
| 03/08/25 | OF Juneiker Caceres assigned to Cleveland Guardians. |
| 03/08/25 | 2B Kyle Dernedde assigned to Cleveland Guardians. |
| 03/08/25 | 2B Yaikel Mijares assigned to Cleveland Guardians. |
| 03/08/25 | Cleveland Guardians optioned RHP Daniel Espino to Columbus Clippers. |
| 03/08/25 | Cleveland Guardians optioned RHP Nic Enright to Columbus Clippers. |
| 03/08/25 | Cleveland Guardians optioned RHP Franco Aleman to Columbus Clippers. |
| 03/07/25 | RF Barrett Riebock assigned to Cleveland Guardians. |
| 03/07/25 | RHP Josh Harlow assigned to Cleveland Guardians. |
| 03/06/25 | SS Christian Knapczyk assigned to Cleveland Guardians. |
| 03/06/25 | CF Guy Lipscomb assigned to Cleveland Guardians. |
| 03/06/25 | Cleveland Guardians signed free agent RHP Tyler Naquin to a minor league contract. |
| 03/04/25 | RHP Kyle Scott assigned to Cleveland Guardians. |
| 03/04/25 | SS Alex Mooney assigned to Cleveland Guardians. |
| 03/04/25 | RF Jonah Advincula assigned to Cleveland Guardians. |
| 03/03/25 | RHP Jay Driver assigned to Cleveland Guardians. |
| 03/03/25 | RF Christopher Espinola assigned to Cleveland Guardians. |
| 03/03/25 | 2B Tyresse Turner assigned to Cleveland Guardians. |
| 03/01/25 | RHP Dylan DeLucia assigned to Cleveland Guardians. |
| 03/01/25 | Cleveland Guardians signed free agent RHP Carlos Sanchez to a minor league contract. |