Astros Roster & Staff
Transactions
| Date | Transaction |
| 04/11/25 | Atlanta Braves traded RHP Patrick Halligan to Houston Astros. |
| 04/09/25 | Houston Astros signed free agent RHP Garrett Apker to a minor league contract. |
| 04/09/25 | Houston Astros signed free agent RHP Cam Brown to a minor league contract. |
| 04/09/25 | Houston Astros sent RHP Forrest Whitley on a rehab assignment to Sugar Land Space Cowboys. |
| 04/08/25 | Houston Astros activated LHP Bennett Sousa. |
| 04/08/25 | Houston Astros sent RHP Kaleb Ort on a rehab assignment to Sugar Land Space Cowboys. |
| 04/08/25 | Houston Astros placed RHP Spencer Arrighetti on the 15-day injured list retroactive to April 7, 2025. Broken Right Thumb. |
| 04/08/25 | Houston Astros traded RHP Rafael Montero and cash to Atlanta Braves for Player To Be Named Later. |
| 04/08/25 | Houston Astros recalled LHP Bennett Sousa from Sugar Land Space Cowboys. |
| 04/08/25 | Houston Astros recalled RHP Luis Contreras from Sugar Land Space Cowboys. |
| 04/07/25 | Houston Astros transferred RHP Luis Garcia from the 15-day injured list to the 60-day injured list. Right elbow soreness. |
| 04/07/25 | Houston Astros optioned RHP Luis Contreras to Sugar Land Space Cowboys. |
| 04/07/25 | Houston Astros selected the contract of RHP Logan VanWey from Sugar Land Space Cowboys. |
| 04/05/25 | Houston Astros sent RHP Lance McCullers Jr. on a rehab assignment to Corpus Christi Hooks. |
| 04/04/25 | Houston Astros signed free agent SS Reylin Perez to a minor league contract. |
| 04/03/25 | LF Cooper Hummel elected free agency. |
| 04/03/25 | Houston Astros signed free agent RHP Ricardo Heredia to a minor league contract. |
| 04/01/25 | Houston Astros transferred RHP Cristian Javier from the 15-day injured list to the 60-day injured list. Recovery from Tommy John surgery. |
| 04/01/25 | Toronto Blue Jays traded RHP Nick Robertson to Houston Astros for RHP Edinson Batista. |
| 04/01/25 | Toronto Blue Jays traded RHP Nick Robertson to Houston Astros for RHP Edinson Batista. |